Glass Health

Glass Health is a clinical decision support platform aimed at clinicians rather than patients. A physician enters a clinical picture and Glass generates a ranked differential diagnosis and an evidence-based diagnostic and treatment plan, with the reasoning laid out for the clinician to evaluate; it has also added ambient documentation. A Y Combinator company, Glass reported use by more than 100,000 US residents, trainees, and attending physicians, and in 2026 overhauled its platform, pricing, and enterprise offering. It sits alongside catalogued OpenEvidence as a physician-facing decision-support tool, distinguished by its differential-diagnosis workflow. The essential framing is that Glass supports clinical reasoning — surfacing possibilities and evidence — while the licensed clinician makes the decision and bears responsibility; hallucination and over-reliance are the risks it must manage.