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4 min read·Updated March 27, 2026

Tempus AI is a clinical AI and precision medicine company with the largest multimodal clinical dataset in the industry — 40+ million records powering genomic testing, AI oncology tools, and data licensing at $1.27 billion revenue.

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Learning Objectives

  • Understand what Tempus AI does and how clinical AI improves cancer treatment decisions
  • Evaluate Tempus's data platform, genomic testing, and AI software capabilities
  • Assess Tempus's business model combining diagnostics revenue with data licensing

What Is Tempus AI?

Tempus AI (NASDAQ: TEM) is a clinical AI and precision medicine company that helps oncologists select the most effective targeted therapies for individual cancer patients. The platform combines genomic testing (analyzing a patient's tumor DNA), AI software (interpreting results and recommending treatments), and the largest multimodal clinical dataset in the industry — 40+ million records connected via 4,500+ integrations.

With $1.27 billion in 2025 revenue (+83% year-over-year) and an $8.9 billion market cap, Tempus is one of the largest AI healthcare companies.

Key Products

ProductWhat It Does
xT (Tumor DNA)Comprehensive genomic profiling from solid tumor tissue
xF (Liquid Biopsy)Blood-based cancer detection and monitoring
xR (RNA)RNA sequencing for treatment selection
Tempus OneGenerative AI clinical assistant integrated into EHR systems
Tempus NextCare pathway intelligence platform (expanded to breast cancer 2025)
Tempus xMLiquid biopsy for minimal residual disease and immunotherapy response

Company Details

DetailInfo
CompanyTempus AI Inc. (NASDAQ: TEM)
CEOEric Lefkofsky (co-founder)
HeadquartersChicago, Illinois
IPOJune 2024
Revenue (2025)$1.27 billion (+83% year-over-year)
Market Cap~$8.9 billion
Clinical Records40+ million connected via 4,500+ integrations
Websitetempus.com

Key Takeaways

  • Tempus combines genomic testing, AI software, and the largest clinical dataset (40+ million records) to help oncologists choose the most effective cancer treatments
  • $1.27 billion revenue growing 83%; uniquely positioned at the intersection of diagnostics and AI data licensing
  • Competes with Foundation Medicine (Roche), Guardant Health, and Illumina in genomics; unique in combining testing revenue with data platform

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